gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The BCMA×CD3 bispecific antibody binds BCMA on target cells and CD3 on T cells, bringing them together and activating T cells to kill BCMA-expressing cells via perforin/granzyme-mediated cytotoxicity.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Expressed on antibody-secreting plasma cells/plasmablasts
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06369467
disease_id_num_tar_ref
711
drug_id_num_tar_ref
1975