gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Linvoseltamab binds CD3ε on T cells to activate and redirect them toward BCMA-expressing cells, which are then killed via T‑cell cytolysis (perforin/granzymes). CD3+ T cells themselves are not targeted for killing.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Component of T-cell receptor/CD3 complex on T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06369467
disease_id_num_tar_ref
711
drug_id_num_tar_ref
1975