gene_symbol
FAM53B
hgnc_id
HGNC:28968
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
DC vaccine primes antigen-specific CD8+ T cells that recognize HLA-A*02:01-presented CircFAM53B-219aa peptide on tumor cells and kill them via perforin/granzyme-mediated apoptosis.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
HLA-A*02:01-restricted MHC class I epitope encoded by circular RNA
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06530082
disease_id_num_tar_ref
4
drug_id_num_tar_ref
8