gene_symbol
TPBG
hgnc_id
HGNC:12004
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-5T4 antibody-drug conjugate binds 5T4, is internalized, and releases an intracellular cytotoxic payload that kills 5T4-expressing cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
biparatopic (binds two distinct epitopes)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06667960
disease_id_num_tar_ref
861
drug_id_num_tar_ref
2367