gene_symbol
IL2RA
hgnc_id
HGNC:6008
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Antithymocyte polyclonal IgG binds CD25 on T cells and triggers complement-dependent lysis and Fc-mediated ADCC/opsonophagocytosis, leading to lysis/apoptosis of CD25+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell activation marker
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06374095
disease_id_num_tar_ref
890
drug_id_num_tar_ref
2428