gene_symbol
MICA
hgnc_id
HGNC:7090
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
nCTLs express NKG2D that recognizes MICA on target cells, activating cytotoxic granule release (perforin/granzyme) and causing direct lysis/apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
NKG2D ligand
trial_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT03735589
disease_id_num_tar_ref
987
drug_id_num_tar_ref
2707