gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BCMA-specific CAR T cells bind BCMA on target cells, become activated, and directly kill via perforin/granzyme-mediated cytolysis (and death-receptor pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Membrane-bound antigen on malignant plasma cells; MHC-independent CAR recognition
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05801939
disease_id_num_tar_ref
1010
drug_id_num_tar_ref
2760