gene_symbol
TNFRSF4
hgnc_id
HGNC:11918
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
IgG1 Fc engages effector cells to mediate ADCC (and related Fc-effector functions), depleting OX40+ T cells bound by the antibody.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
TNFRSF family costimulatory receptor on activated T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06438263
disease_id_num_tar_ref
1068
drug_id_num_tar_ref
2903