gene_symbol
GPRC5D
hgnc_id
HGNC:13310
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Bispecific antibody bridges CD3+ T cells to GPRC5D+ cells, triggering T-cell cytotoxicity via immune synapse formation and perforin/granzyme-mediated killing.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface GPCR on myeloma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06205823
disease_id_num_tar_ref
2105
drug_id_num_tar_ref
5627