Rabbit polyclonal anti-T-cell globulin used for in vivo T-cell depletion and immunosuppression.
Rabbit polyclonal anti‑thymocyte globulin that binds multiple T‑cell surface antigens (e.g., CD2, CD3, CD4, CD8, adhesion/HLA molecules) and depletes T lymphocytes via complement‑dependent cytotoxicity, antibody‑dependent cellular cytotoxicity, and apoptosis, resulting in potent in vivo T‑cell immunosuppression.
YES
DIRECT
Rabbit polyclonal antibodies bind CD2 on T cells, triggering complement-dependent cytotoxicity and Fc-mediated ADCC, and can induce apoptosis, leading to direct depletion of CD2+ cells.
Rabbit polyclonal anti-T-cell globulin used for in vivo T-cell depletion and immunosuppression.
Rabbit polyclonal anti‑thymocyte globulin that binds multiple T‑cell surface antigens (e.g., CD2, CD3, CD4, CD8, adhesion/HLA molecules) and depletes T lymphocytes via complement‑dependent cytotoxicity, antibody‑dependent cellular cytotoxicity, and apoptosis, resulting in potent in vivo T‑cell immunosuppression.
YES
DIRECT
Polyclonal antibodies bind CD3 on T cells and deplete them via complement-dependent cytotoxicity, Fc-mediated ADCC, and induction of apoptosis.
Rabbit polyclonal anti-T-cell globulin used for in vivo T-cell depletion and immunosuppression.
Rabbit polyclonal anti‑thymocyte globulin that binds multiple T‑cell surface antigens (e.g., CD2, CD3, CD4, CD8, adhesion/HLA molecules) and depletes T lymphocytes via complement‑dependent cytotoxicity, antibody‑dependent cellular cytotoxicity, and apoptosis, resulting in potent in vivo T‑cell immunosuppression.
YES
DIRECT
Rabbit anti-thymocyte globulin binds CD4 on T cells, opsonizing them and inducing complement-dependent lysis, Fc-mediated ADCC by NK/macrophages, and apoptosis, leading to direct depletion of CD4+ cells.
Rabbit polyclonal anti-T-cell globulin used for in vivo T-cell depletion and immunosuppression.
Rabbit polyclonal anti‑thymocyte globulin that binds multiple T‑cell surface antigens (e.g., CD2, CD3, CD4, CD8, adhesion/HLA molecules) and depletes T lymphocytes via complement‑dependent cytotoxicity, antibody‑dependent cellular cytotoxicity, and apoptosis, resulting in potent in vivo T‑cell immunosuppression.
YES
DIRECT
Antibodies in rabbit anti-thymocyte globulin bind CD8α on T cells and trigger complement-dependent lysis and Fc-mediated ADCC, and can induce apoptosis, depleting CD8+ cells.